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The horses were treated orally b. With clenbuterol (as Ventipulmin Syrup), beginning with the lowest dosage of 0. On day 10 of treatment at the effective dose (0. 2 micrograms/kg), treatment was either withdrawn (Schedule A) or continued for an additional 20 days (Schedule B). Summary Horses with anhidrosis are defined by signs of impaired thermoregulation caused by sweating that is inadequate for the ambient conditions. Anhidrosis has been recognised since the early twentieth century; affected horses have been variably described as nonsweaters, drycoats, blowers or puffers. A new study at UF is investigating the sweat genes of the horse and their genetic association to anhidrosis. If you own a horse that has been diagnosed with anhidrosis, please contact the Brooks Equine Genetics Lab for more information. You may also call (352) 273-8080 or email equinegenetics@ifas. Horses with long-standing anhidrosis may reveal dry, flaky skin, hair loss, lethargy, anorexia, and a decreased water intake. Areas on the body that may retain the ability to sweat include those under the mane, in the saddle and halter areas, and in the perineal regions. Abstract Case Description—3 Quarter Horse racehorses were examined for suspected clenbuterol overdose 12 to 24 hours after administration by mouth of a compounded clenbuterol product. Clinical Findings—All horses developed sinus tachycardia, muscle tremors, hyperhidrosis, and colic. 5%) or plasma (3. 0%) of the clenbuterol-treated horses without exercise training were found, suggesting the antiergogenic effect of chronic clenbuterol administration in athletic horses is a result of interaction with exercise. Conclusion Clenbuterol has effects in multiple body systems and tissues 
 

Abstract Objective—To determine whether prolonged administration of clenbuterol results in tachyphylaxis, specifically regarding its bronchoprotective properties and effect on sweating in horses. Animals—8 Thoroughbreds with inflammatory airway disease. Procedures—In a crossover design, horses received clenbuterol (0. Clenbuterol is effective in causing sweating in some anhidrotic horses. Background: clenbuterol is a type 3 b-agonist that has been. Study of the sympathetic nerve fibres in diabetic anhidrosis. Not for use in horses hypersensitive (allergic) to clenbuterol. Do not use in horses with heart disease or anhidrosis (inability to sweat properly). Anhidrosis refers to a temporary or complete loss of the ability to sweat (Breuhaus 2009). In horses, it is characterized by the reduced or lack of sweat response to increased body temperature. This is a poorly understood condition with a varying prevalence in the horse population. Abstract Case Description—3 Quarter Horse racehorses were examined for suspected clenbuterol overdose 12 to 24 hours after administration by mouth of a compounded clenbuterol product. Clinical Findings—All horses developed sinus tachycardia, muscle tremors, hyperhidrosis, and colic. The horses were treated orally b. With clenbuterol (as Ventipulmin Syrup), beginning with the lowest dosage of 0. On day 10 of treatment at the effective dose (0. 2 micrograms/kg), treatment was either withdrawn (Schedule A) or continued for an additional 20 days (Schedule B). Occasionally, and often inexplicably, a horse will lose its ability to sweat, a condition known as anhidrosis. As with humans, sweating among horses is key to thermoregulation, so anhidrotic horses, sometimes called “non-sweaters,” pose significant challenges for their owners 
 
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